Bio-Boost is a concentrated source of viable strains of probiotic microorganisms and nutraceutical compounds. To achieve efficiency and production improvements in monogastric species and young ruminants.

Optimization of rumen fermentation, including maximizing rumen fiber digestion and microbial synthesis while minimizing protein degradation, ammonia and methane production is a core aim for an effective probiotic. Certain strains of the yeast Saccharomyces cerevisiae can improve rumen fermentation, thereby increasing animal production. Some strains of S. cerevisiae can survive through the harsh environments of extreme pH and digestive enzymes. In the GIT they can suppress pathogenic activities by binding pathogenic cells to their cell surface, facilitating their removal from the gut and stimulating the host animals immune system.

The intestinal tract of a ruminant animal is the site of nutrient digestion and absorption. It is also the site for colonization by both beneficial and pathogenic microorganisms. The microbial balance determines the host animal’s health status. In healthy animals, lactobacilli dominate the intestine with a population of >100,000 cfu/g and successfully suppress pathogenic activity. A residual flora of less than 0.01% of the total microbial population is composed of clostridia, staphylococci, pseudomonads, proteus and yeasts of the Candida genus. Changes in this balance of microbial composition often occur and represent a major cause of digestive disturbance. This is frequently due to the development of Gram negative bacteria, particularly pathogenic E. coli strains.

Therapeutic treatment of a sick animal with antibiotics or other drugs may remove all the microbes in the intestine and create a temporarily sterile digestive tract. Animals are extremely vulnerable to invasion by pathogenic organisms immediately after such therapeutic treatment. It has been shown that supplementing with certain strains of lactobacilli can help animals to resist stress and post-antibiotic problems. The strain of Lactobacillus acidophilus chosen for Bio-Boost was specifically selected for its positive attributes in this area.

Characteristics of Bio-Boost include:

Performance	Survivability
rapid growth rate	good bile resistance
short lag phase from reactivation	high freeze drying survival rates
high lactic acid production	excellent antibiotic resistance
effective intestinal adhesion	good long-term stability
ideal carbohydrate fermentation profile

Effect of Bio-Boost on Calves

Modes of Action of Bio-Boost

• Competitive Exclusion:
  Bacteria attach to specific sites on intestinal wall by adhering to epithelial cells or the mucus covering them, thereby excluding undesirable bacteria.


• Production of Acids:
  For example, lactic acid, decreasing the pH and inhibiting bacterial development e.g. E. coli.


• Production of Anti-Microbial Substances:
  Such as hydrogen peroxide and bacteriocins.


• Consumption of Available Nutrients:
  At the expense of the undesirable bacteria, effectively inhibiting growth by starvation.


• Detoxification:
  In-situ neutralization of enter-toxins and prevention of toxic amine synthesis. Binding of pathogens.


• Stimulation of the immune system:
  MOS and lactic bacteria stimulate both the systemic immune response and secretory immune system.

Storage

Probiotic products contain live microorganisms. These microbials are usually freeze-dried and in a dormant stage but their viability is very vulnerable to exposure to high temperatures and humidity. Under refrigeration conditions (c40°F) microbial metabolic activity is suspended thereby extending shelf life stability. Bio-Boost should be stored with care to ensure maximum effect.

Bio-Boost is packaged in units of 500g, 1500g and 6000g providing 100, 300 and 1200 doses respectively of 5g per head per day.

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